Not many people are aware that taking medication with grapefruit juice can be deadly. A new research says that over the four years, the number of medications that could have a bad reaction to grapefruit juice has increased.
Under normal circumstances, eating a grapefruit or drinking grapefruit juice is a very welcomed boost of Vitamin C. But as it turns out, when you’re making the wrong combination, your fresh grapefruit juice could bring your death. Sounds grim indeed, but a research team with Western University in London, Ontario, says there are more than 85 oral medications that could have a bad reaction with grapefruit juice.
“Many of the drugs that interact with grapefruit are highly prescribed and are essential for the treatment of important or common medical conditions” reads the research. Not all of them will trigger a bad reaction to the grapefruit juice that will lead to your death, but at least 43 will trigger serious effects.
The number of medications that interacts negatively with the grapefruit juice has risen from 17 to 43. Basically, “half of these drugs actually can cause sudden death” researchers warn. Given that we’re talking about highly popular drugs, it’s all the most important for people to know getting their medication with grapefruit juice could trigger severe reactions such as respiratory failure and gastrointestinal bleeding among others.
“Your urine looks like wine. You can be in such extreme pain that you literally can’t walk across the room and your kidneys have totally shut down” one of the lead researchers told The Calgary Herald.
On that list are drugs usually prescribed to lower cholesterol (Lipitor, Zocor, Mevacor, Altoprev) or popular medications for people with cardiovascular problems. Even several anti-psychotic and pain drugs might interact badly with the grapefruit juice. So, what’s in the grapefruit juice that triggers such bad reactions with certain medications?
The grapefruit has a chemical that hinders the body’s ability to absorb the drug. “We know it boosts drug levels in the blood” said lead researcher David Bailey. “Now you’re seeing so many drugs where the levels get boosted that the consequences are really quite dire” he added.
And it doesn’t even take a great intake of grapefruit juice to cause a reaction. “You can be taking one grapefruit a day or just drinking 250 milliliters. But the magnitude of the increase in some individuals can be so large that you can precipitate this adverse event”.